A meta-analysis of studies on psilocybin show that high doses of the substance can alleviate symptoms of depression in people at levels comparable to the SSRI drug escitalopram, which is used to treat major depressive episodes. Researchers found that patients fared better with psilocybin - the active ingredient in 'magic mushrooms' - than with placebos. [...]

It's not often that a scientist becomes a subject for his own research; even less common when said scientist describes his brain as 'breaking' during the experiment. But that's precisely how Dr. Nico Dosenbach, an associate professor of neurology at Washington University School of Medicine in St. Louis, recounted his experience under the influence of [...]

Over the course of a given day, you likely will experience tens of thousands of thoughts. It should go without saying that it is these thoughts that make up your sense of reality and your role in it. But here's the thing: the vast majority of your thoughts are not only repetitious, they're negative. We're [...]

Everywhere you turn, it seems, psychological sufferers - including a growing number of therapists and physicians treating them - are turning to psychedelics or, more specifically, 'psychedelic-assisted therapy,' to cure suffering. At the risk of harshing a lot of people's buzzes, it's unlikely that MDMA, psilocybin, ketamine, LSD, ayahuasca and a host of other mind-bending [...]

The 4 a.m. anxiety wake-up call. Shit, not again. The mental engine sparks to life and like that the mind is a whirl of anxious thoughts and fears about this person or that, regrets about the past, apprehension about the future, money, kids, health. It's as if they've been waiting there in the darker corners [...]

In the spring of 1999 I and another member of the American Red Cross boarded a flight bound for the Balkan conflict in Kosovo. A veteran of many humanitarian assignments, I felt no particular concern about the trip. But on the evening of my departure the chronic anxiety that had become a part of my [...]

Imagine that you are an actor and the director calls with a new assignment. It goes something like this: “We’re sending you into a new theatre for the role of a lifetime.” So far, so good. “But be forewarned you are joining a hostile cast and some of the other actors may not be welcoming [...]

A bit of a departure today, maybe because it's rainy and gray out, maybe because it seems to me a lot of us need a bit more music and joy in our lives and a lot less anger and division. When I was a child there was a lot of music in the home and [...]

Few of us in this day and age haven’t heard the expression, “What you put your mind to is what you become” or “Your thoughts are things so be careful with your thoughts,” or some version of the same. Thus the more motivated of us walk around thinking, “Gotta be careful what I think.” The [...]